Key Points
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ARKK surged 153% in 2020 then plunged 67% in 2022 before recovering 37.33% in the last year.
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Tesla remains Wood’s largest position at $1.3B, representing 9% of the fund.
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Wood kept buying beaten-down stocks during the decline rather than changing her investment approach.
The analyst who called NVIDIA in 2010 just named his top 10 AI stocks. Get them here FREE.
Few big investors have managed to stay relevant through the tumultuous market cycles the market has been through since 2020. Cathie Wood gained fame as the founder of the ARK Innovation ETF (BATS:ARKK). It gained 153% in 2020, and billions poured in from first-time buyers who noticed her conviction-laden buys paying off.
The magic dissolved as quickly as it had appeared. When the Federal Reserve pivoted to fight inflation, the expensive, profit-light growth companies Wood loved were the first to be sold. The flagship fund declined 23% in 2021 and 67% in 2022. However, Wood never abandoned the strategy that made her famous.
She kept buying more of the beaten-down names and learned from her earlier failures. The stubbornness worked out as the market has bounced back. ARKK is up 37.33% for the last year (as of March 5), and Wood is once again gaining popularity on Wall Street.
Wood’s ARK Innovation ETF roughly has $6.52b in assets as of today. Of that enormous fortune, here are the top 10 stocks she is betting on. In classic Cathie Wood fashion, they are high on tech, innovation, and potential for the future.
#10 Tempus AI Inc. (TEM)
Tempus offers AI-powered precision medicine, using AI to analyze clinical and molecular data to personalize cancer treatment and improve patient outcomes. The company has growing partnerships with healthcare systems and expanding AI usage in oncology.
Wood increased her position in TEM by 5.32% in the fourth quarter of 2025. She now owns $446 million in shares, representing 2.96% of the overall portfolio. TEM stock is down 3.86% in the last year, as of March 5.
#9 Teradyne Inc. (TER)
Teradyne specializes in equipment testing and advanced robotics, and customers include Samsung, Intel, and IBM. Many analyst rate TER a “buy.”
Wood decreased her position by 13.45% in Q4, and now owns shares valued at $456 million (about 3% of the fund). Teradyne is up 52.59% year to date.
#8 Robinhood (HOOD)
Offering financial technology and brokerage services, Robinhood is disrupting traditional brokerage with commission-free trading and crypto trading. It’s very popular with younger people.
ARK Innovation slightly decreased its exposure in Q4, owning $544 million (3.61% of the fund). HOOD stock was up 64.9% in the last year.
#7 Advanced Micro Devices (AMD)
AMD is an AI chipmaker alternative to Nvidia with higher potential upside. If AMD can capture a big portion of market share, it can lead to significant gains.
Wood is still a believer in AMD, which comprises 3.66% of her portfolio ($551 million). But she did sell 483,000 shares in the fourth quarter of 2025. AMD stock was up 92.09% in the last year.
#6 CRISPR Therapeutics (CRSP)
CRISPR offers revolutionary gene editing technology with the potential to cure genetic diseases and transform healthcare. Positive catalysts include clinical trial successes and FDA approvals for gene therapies.
Wood bought more CRSP shares in the fourth quarter, now owning $552 million (3.67% of the portfolio. CRSP is up 8.79% YTD.
#5 Palantir Technologies (PLTR)
Palantir is the leading AI-powered data analytics platform serving government and commercial clients with sticky, high-margin contracts. Positive catalysts include an expanding commercial customer base and increasing AI integration.
Wood decreased her exposure to PLTR by nearly 20% in Q4, but still owns stocks valued at $574 million. That’s 3.82% of the ARK fund. PLTR stock is up 67.22% in the last year.
#4 Coinbase (COIN)
Coinbase is a leading U.S. cryptocurrency exchange. It should benefit from mainstream crypto adoption and regulatory clarity.
ARKK increased its exposure to COIN by about 6% in the fourth quarter. The ETF holds $575 million in COIN shares (3.82% of overall holdings). Coinbase stock has dropped 10.3% YTD.
#3 Roku (ROKU)
Roku is a leading streaming platform benefiting from cord-cutting trends and a growing connected TV advertising market. Positive catalysts include increasing ad revenue per user and international expansion opportunities.
Wood decreased her exposure to Roku by 20% in Q4, but the stock still accounts for 4.24% of her portfolio ($638 million). ROKU is up 14.39% in the latest one-year period.
#2 Shopify (SHOP)
Shopify is the leading e-commerce infrastructure provider benefiting from digital transformation and small business growth. The company is rolling out AI-powered commerce tools and expanding into enterprise markets.
Wood sold some SHOP stock in Q4 but still owns four million shares valued at $640 million (4.25% of the ARKK fund). SHOP is up about 25% in the last year.
#1 Tesla (TSLA)
Enthusiasm surrounding Tesla’s Optimus robots and an EV sales rebound caused the stock to surge last year. Positive catalysts include a bona fide robot that can do physical tasks, self-driving cars, and a successful robotaxi launch.
Tesla remains Wood’s largest investment by far ($1.3 billion, representing nearly 9% of the ARKK fund). Still she decreased her position by 18.81% in the fourth quarter. TSLA was up 43.43% in the last year.
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