AI, Crypto, and Biopharma Dominate This Week’s Top 20 Biggest Stock Movers
This week, U.S. stocks rallied to near record highs as AI momentum surged, inflation data cooled, and hopes for Federal Reserve rate cuts grew. Investors reacted positively to a mix of upbeat earnings, high volumes of speculative trading, and strong signaling from the Fed. Amid the frenzy, one major stock saw its price rise by more than 200% in just three trading days.
Many of the biggest winners were in the AI, crypto, and biopharma sectors. After a blockbuster licensing deal with RemeGen worth up to $4 billion, Vor Biopharma (VOR) surged 206.9% from June 23 to June 26. Plus Therapeutics stock doubled in price after the company received FDA clearance to begin clinical trials of its targeted radiotherapy for childhood brain cancer, while QuantumScape jumped 80.4% after unveiling its "Cobra" breakthrough for solid-state battery production. A closer look at the data reveals the 20 biggest stock winners this week.
To determine the 20 biggest stock winners this week, My Investing News reviewed closing prices for the past week for over 11,000 stocks. Stocks traded in U.S. markets were ranked based on the percentage change in closing price from June 23 to June 26, 2025. Only companies with daily trading volumes above 10 million shares were considered.
20. Plug Power Inc. (PLUG)
- Change in closing price, June 23 to June 26: +11.9%
- Closing price, June 23: $1.09
- Closing price, June 26: $1.22
- Average daily trade volume: 115,280,282
- Industry: Electrical Equipment & Parts
19. Marvell Technology, Inc. (MRVL)
- Change in closing price, June 23 to June 26: +13.0%
- Closing price, June 23: $70.78
- Closing price, June 26: $79.97
- Average daily trade volume: 21,615,050
- Industry: Semiconductors
18. SES AI Corporation (SES)
- Change in closing price, June 23 to June 26: +13.3%
- Closing price, June 23: $0.83
- Closing price, June 26: $0.94
- Average daily trade volume: 12,841,108
- Industry: Auto Parts
17. Riot Platforms, Inc. (RIOT)
- Change in closing price, June 23 to June 26: +13.4%
- Closing price, June 23: $9.27
- Closing price, June 26: $10.51
- Average daily trade volume: 33,499,946
- Industry: Capital Markets
16. New Fortress Energy Inc. (NFE)
- Change in closing price, June 23 to June 26: +16.7%
- Closing price, June 23: $2.04
- Closing price, June 26: $2.38
- Average daily trade volume: 11,526,238
- Industry: Oil & Gas Midstream
15. Hertz Global Holdings, Inc. (HTZ)
- Change in closing price, June 23 to June 26: +17.8%
- Closing price, June 23: $6.42
- Closing price, June 26: $7.56
- Average daily trade volume: 17,787,806
- Industry: Rental & Leasing Services
14. Cipher Mining Inc. (CIFR)
- Change in closing price, June 23 to June 26: +18.7%
- Closing price, June 23: $3.53
- Closing price, June 26: $4.19
- Average daily trade volume: 19,476,795
- Industry: Capital Markets
13. Super Micro Computer, Inc. (SMCI)
- Change in closing price, June 23 to June 26: +20.5%
- Closing price, June 23: $40.89
- Closing price, June 26: $49.27
- Average daily trade volume: 48,123,383
- Industry: Computer Hardware
12. Coinbase Global, Inc. (COIN)
- Change in closing price, June 23 to June 26: +21.9%
- Closing price, June 23: $307.59
- Closing price, June 26: $375.07
- Average daily trade volume: 12,595,246
- Industry: Financial Data & Stock Exchanges
11. CleanSpark, Inc. (CLSK)
- Change in closing price, June 23 to June 26: +22.1%
- Closing price, June 23: $8.85
- Closing price, June 26: $10.81
- Average daily trade volume: 26,686,782
- Industry: Capital Markets
10. Ondas Holdings Inc. (ONDS)
- Change in closing price, June 23 to June 26: +22.4%
- Closing price, June 23: $1.43
- Closing price, June 26: $1.75
- Average daily trade volume: 12,963,003
- Industry: Communication Equipment
9. TeraWulf Inc. (WULF)
- Change in closing price, June 23 to June 26: +23.0%
- Closing price, June 23: $3.57
- Closing price, June 26: $4.39
- Average daily trade volume: 40,454,170
- Industry: Capital Markets
8. Sunrun Inc. (RUN)
- Change in closing price, June 23 to June 26: +24.2%
- Closing price, June 23: $6.24
- Closing price, June 26: $7.75
- Average daily trade volume: 21,344,075
- Industry: Solar
7. Lexicon Pharmaceuticals, Inc. (LXRX)
- Change in closing price, June 23 to June 26: +27.4%
- Closing price, June 23: $0.73
- Closing price, June 26: $0.93
- Average daily trade volume: 13,705,353
- Industry: Biotechnology
6. BigBear.ai Holdings, Inc. (BBAI)
- Change in closing price, June 23 to June 26: +38.8%
- Closing price, June 23: $4.18
- Closing price, June 26: $5.80
- Average daily trade volume: 91,328,217
- Industry: Information Technology Services
5. Core Scientific, Inc. (CORZ)
- Change in closing price, June 23 to June 26: +44.1%
- Closing price, June 23: $11.35
- Closing price, June 26: $16.36
- Average daily trade volume: 14,567,033
- Industry: Software - Infrastructure
4. bioAffinity Technologies, Inc. (BIAF)
- Change in closing price, June 23 to June 26: +56.5%
- Closing price, June 23: $0.23
- Closing price, June 26: $0.36
- Average daily trade volume: 15,846,393
- Industry: Diagnostics & Research
3. QuantumScape Corporation (QS)
- Change in closing price, June 23 to June 26: +80.4%
- Closing price, June 23: $4.24
- Closing price, June 26: $7.65
- Average daily trade volume: 17,092,032
- Industry: Auto Parts
2. Plus Therapeutics, Inc. (PSTV)
- Change in closing price, June 23 to June 26: +105.6%
- Closing price, June 23: $0.18
- Closing price, June 26: $0.37
- Average daily trade volume: 23,524,012
- Industry: Biotechnology
1. Vor Biopharma Inc. (VOR)
- Change in closing price, June 23 to June 26: +206.9%
- Closing price, June 23: $0.29
- Closing price, June 26: $0.89
- Average daily trade volume: 11,754,725
- Industry: Biotechnology